Intensive Insulin Therapy in Intensive Care: An Example of the Struggle to Implement Evidence-Based Medicine

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Intensive Insulin Therapy in Intensive Care: An Example of the Struggle to Implement Evidence-Based Medicine

A long with improving patients' safety and reducing medical errors, one of the main challenges in medicine is implementing new strategies that have the potential to improve health outcomes. After the process of critically appraising clinical trials has fi nished, and the results of this appraisal are used to guide changes in clinical practice, it is then time to critically appraise the success ...

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Intensive insulin therapy in the intensive care unit.

Several studies have shown that elevated glucose concentrations in patients with acute coronary syndrome and other acute severe illnesses are associated with increased short- and long-term all-cause and cardiovascular mortality (CVM). This has subsequently led to the use of intensive insulin therapy (IIT) to control hyperglycemia. Earlier studies have shown that the prevention of hyperglycemia ...

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Insulin therapy of hyperglycemia in intensive care.

BACKGROUND Hyperglycemia is common among patients admitted to intensive care units, and carries the risk for complications and prolonged ICU stay. With intensive insulin control of blood glucose, morbidity and mortality can be reduced. OBJECTIVES To determine whether intensive or conventional insulin control of blood glucose in hyperglycemic ICU patients correlated with the prognosis. METHO...

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Insulin therapy within the intensive care unit

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ژورنال

عنوان ژورنال: PLoS Medicine

سال: 2006

ISSN: 1549-1676

DOI: 10.1371/journal.pmed.0030456